/*******20061114*********/ Biacore Edition SPOCLE Generator 1.1.04 Following modifications have been added to Biacore Edition SPOCLE Generator 1.1.03 1.) Now users can decide weather they want to register with Spotsupport or not in the first run of the program. If any user select no and if he feels he need to register with Spotsupport, there is a option in the About window. 2.) During Downloading of the new version now user can select where he want to save the Downloading files. And the Download process is resume supported. /*******20060609*********/ Biacore Edition SPOCLE Generator 1.1.03 Foloowing modifications have been added to the Biacore Edition SPOCLE Generator 1.1.02 1.) In the Wash/Dry panel Last wash dry cycle was not set to a different wash dry time by defalut. this was fixed so the program sets the last wash dry cycle to a different times. /*******20060608*********/ Biacore Edition SPOCLE Generator 1.1.02 Foloowing modifications have been added to the Biacore Edition SPOCLE Generator 1.1.01 1.) when sample pick is selected the number of spots are displyed incorrectly, this bug is fixed 2.) Pre print spots per sample text box was displaying a number when ther is no pre print slides selected this is fixed. /*******20060608*********/ Biacore Edition SPOCLE Generator 1.1.01 Foloowing modifications have been added to the Biacore Edition SPOCLE Generator 1.1.00 1.) Bug fixed Spotting was not done for even wells and this was fixed 2.) Import Sample pick list option is added to the Plates panel Users can import a pre processed sample pick list file (according to the specifications given in the sample pick list file that come with this program) or Users can create his own sample pick list by clicking on relevent wells on the graphical microplate.If user need the this sample pick list for later use he can save it using the given option. /********20060605********/ Biacore Edition SPOCLE Generator 1.1.00 SpotSupport Registration V 1.0.02 is include with this version. Totally new GUI have been added, and it is much more similer to the Usual SpoCLeGen GUI. To run this program user must have installed Microsoft .NET Framework2 or Later in his/her computer. This program can only be used to generate SPO files that can be used print spots on to specially designed BiaCore Fluidic Cell type substrates Program Operation Start Panel ----------- Users have the option to load a saved user Profile or a start with the default user profile.(*.sgp files) Note that sgp files generated from previous versions are not compatible with this version. Pins panel ---------- Micro Spotting Pin type can be set here, however, Pin center to center distance is set later in the program and is custom set for any Pin type. Once Micro spotting pin is set, standard values for spot spacing and maximum number of spots per loding is set by the program but these can be changed by the user. Pin configuration cannot be changed, only 1X1 configuration is allowed. Plates Panel ------------ The User can set Source plate settings as Full Microplate or as Partial Microplate When selecting a Partial Microplate the bright red well sets the last sample to be picked up from the last plate. Use of catalog number MMP384 from ArrayIt is recommended. . Set the settings for pin reloading and number spots per sample. Samples are printed left to right, top down. Microarrays panel ----------------- Here the user can set the Spot spacing size of the microarray to be printed on the Slide and Lateral and Vertical Offsets from the upper left corner of each “well” of each slide. Substrates Panel ---------------- Here the user can set the substrate's state by clicking on it (status can be print, pre print or unused) and the number of pre prints per sample. Motion panel ------------ Dwell Times for sample loading, pre-printing and printing are set Wash Dry Panel -------------- Here the user can set the parameters desired for cleaning and drying micro spotting pin between samples, between reloading and at the end of the printing routine. Finish panel ------------ User can set the SPO file path or accept the default path The default path is set to the current directory where the program is installed custom SPOCLE file title can be set Users can save the spot map and user profile files by using given options. Spot maps are txt files and can be used in conjunction with Gal File Generator to make GAL files. Contact ArrayIt on how to download and operate Gal File Generator. /********20051229********/ Spocle Generator BiaCore Edition V 1.0.2 Add the Plates panel. which enables customised sample pick from the Source microplate Add the automatic download feature.which will download if a newer version is avilabe in the website. /********20051228********/ Spocle Generator BiaCore Edition V 1.0.1_late Fix the indexing bug in Printing /********20051227********/ Spocle Generator BiaCore Edition V 1.0.1 Fix the following bugs in the V 1.0.0 1.) file save text field now allows users to change the name of the file as required. 2.) Any slide canbe used as a preprint or print slide. 3.) collison of the instrument(while preprinting) when moved in X direction has removed /********20051124********/ Spocle Generator BiaCore Edition V 1.0.0 SPOCLE_GEN special edition (Spocle Generator BiaCore Edition) has been created This program allow to create SPECIAL SPOCLE Language files for the SPOTBOT Now user can print arrays upto 37X37 size on Standard (25mmX76mm) Slide Substrates (the size of the array can be changed if required) but the source Plate is limited to 16X24 microplates and 12X8 well plates